PROfertil® female Study Results
1) embryo quality on day 3 after oocyte retrieval (good quality vs. poor quality) and clinical pregnancy rate.
2) clinical pregnancy rate.
In an intention-to-treat analyses, a higher rate of women with at least one good quality embryo (with at least 6 cells and a fragmentation rate <20%) were found for the study (29/50, 58.0%) compared to the control group (18/50, 36.0%; p = 0.045 in chi-square test; relative risk 1.611, 95% CI 1.009–2.597).
Profertil® female supplementation, given for a minimum of 28 days prior to ovarian hyperstimulation, is beneficial in terms of fertilization rate and embryo quality.
After minimum intake duration, prior to ovarian stimulation, and with no side effects, Profertil® female may:
- significantly increase fertilization rate in comparison to folic acid alone,
- significantly increase embryo quality in comparison to folic acid alone, and
- improve clinical pregnancy rate in comparison to folic acid alone.